Comparison of parathormone lowering effects of paricalcitol and calcitriol in hemodialysis patients

Although the PTH lowering effect of paricalcitol is stronger than calcitriol, both may help maintain PTH levels in the targeted range. Paricalcitol may be preferred for patients who have very high levels of PTH because it seems to cause a faster decline. Calcitriol may be preferred for a slower and limited decline. Prospective further studies with larger samples may be needed for a better comparison.