Tumor-infiltrating neutrophil is an independent prognostic factor in pancreatic ductal adenocarcinoma
TIN in PDAC represents an independent adverse prognostic factor and is likely to be G-MDSCs based on MPO expression. Assessing TIN and MPO status in preoperative biopsy specimens may offer valuable prognostic information and guide future therapeutic strategies for PDAC.
Authors
- H Lee
- Chang Gok Woo (ORCID: https://orcid.org/0000-0001-6565-0555)
- Seung-Myoung Son (ORCID: https://orcid.org/0000-0002-1646-4649)
- Hye Sook Han
- Ok-Jun Lee
Institutions
- Chungbuk National University (KR)
- Seoul Metropolitan Government (KR)
- Chungbuk National University Hospital (KR)
Publication Details
- Journal
- Diagnostic Pathology
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s13000-025-01743-x
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chungbuk National University