Efficacy and Safety of Adjunctive Cenobamate in Chinese Participants with Focal Seizure

Cenobamate demonstrated a very favorable efficacy and safety profile in Chinese participants with focal seizures. The combination of cenobamate with both SCB and non-SCB treatments was effective in reducing seizure frequency and improved responder rates compared to placebo.

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Publication Details

Journal
Advances in Therapy
Published
2025-12-22
DOI
https://doi.org/10.1007/s12325-025-03432-z
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
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article

Efficacy and Safety of Adjunctive Cenobamate in Chinese Participants with Focal Seizure

S. Pan, Yanran Liang, Shuli Zhu, Bing Qin et al.
Advances in Therapy
Epilepsy research and treatment
article

Efficacy and Safety of Adjunctive Cenobamate in Chinese Participants with Focal Seizure

S. Pan, Yanran Liang, Shuli Zhu, Bing Qin, Z L Hu, Cui Li, Weiping Liao, Xiong Han, Luoqing Li, Hongbin Sun, Wang Xuefeng, Xin Wu, Huisheng Chen, Zhen Hong, Bo Xiao, Yanbing Han, Liou Tang, Qifu Li, Peimin Yu, Meiyun Zhang, Ming Zhang, Yutong Liu, Juan Feng, Yangmei Chen, Huapin Huang, Tiancheng Wang, Huiqin Xu, Hui Ye, Dong Zhou
article en

Abstract

Cenobamate demonstrated a very favorable efficacy and safety profile in Chinese participants with focal seizures. The combination of cenobamate with both SCB and non-SCB treatments was effective in reducing seizure frequency and improved responder rates compared to placebo.

Advances in TherapyVol. 43(2)
Qingdao University (CN), Fujian Medical University (CN), Central South University (CN), Nanchang University (CN), Sun Yat-sen University (CN), Dalian Medical University (CN), Jilin University (CN), Sichuan University (CN), Fudan University (CN), Kunming Medical University (CN), Wenzhou Medical University (CN), Tianjin First Center Hospital (CN), First Affiliated Hospital of Wenzhou Medical University (CN), Wuhan University (CN), West China Hospital of Sichuan University (CN), Second Affiliated Hospital of Guangzhou Medical University (CN), Sun Yat-sen Memorial Hospital (CN), Second Affiliated Hospital of Chongqing Medical University (CN), Shanghai University of Traditional Chinese Medicine (CN), Second Affiliated Hospital of Nanchang University (CN), Affiliated Hospital of Qingdao University (CN), Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN), First Affiliated Hospital of Kunming Medical University (CN), Lanzhou University Second Hospital (CN), First Hospital of Jilin University (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), General Hospital of Shenyang Military Region (CN), Yueyang Second People's Hospital (CN), Shanghai Chengtou (China) (CN), Yueyang Hospital (CN), Henan Provincial People's Hospital (CN), Renmin Hospital of Wuhan University (CN), Second Xiangya Hospital of Central South University (CN), Huashan Hospital (CN), Xiangya Hospital Central South University (CN), Tongji Hospital (CN), First Affiliated Hospital of Jinan University (CN), Union Hospital (CN), Huazhong University of Science and Technology (CN), Tianjin Medical University (CN), Lanzhou University (CN), Hainan Medical University (CN), Chongqing Medical University (CN), China Medical University (CN), Guangzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 37%
Epilepsy research and treatment
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