Establishment of a transdermal infection model with Leishmania amazonensis
This novel microneedle infection model enables efficient challenge and reduces risks during animal experimentation. This technique holds promise for future studies of leishmaniasis therapy and vaccine development.
Authors
- Luciana Polaco Covre (ORCID: https://orcid.org/0000-0001-5877-0137)
- Célio Geraldo Freire-de-Lima (ORCID: https://orcid.org/0000-0002-4148-3657)
- Elias Barbosa da Silva-Júnior (ORCID: https://orcid.org/0000-0001-7953-6948)
- Alessandra Marcia da Fonseca-Martins (ORCID: https://orcid.org/0000-0003-2043-2217)
- Alisson Amaral Da-Rocha
- Hozany Praxedes
- Igor Bittencourt dos Santos
- Daniel Claudio Oliveira Gomes
- Douglas Barroso de Almeida
- Naiara Carla Manhães
- Herbert Leonel de Matos Guedes
- Alda M. da-Cruz
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Universidade do Estado do Rio de Janeiro (BR)
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (BR)
- Universidade Federal do Espírito Santo (BR)
- Fundação Oswaldo Cruz (BR)
- Universidade Federal do Estado do Rio de Janeiro (BR)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1186/s13071-025-07127-w
- Primary Topic
- Advancements in Transdermal Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00