Decoding the Mechanisms of Pigment Reduction and Skin Rejuvenation Induced by Picosecond Laser: Insights From a Porcine Model
Picosecond lasers effectively induced pigment reduction, immune-mediated clearance and melanogenesis inhibition, while concomitantly promoting dermal regeneration and epidermal barrier repair. These findings provide mechanistic insights into their therapeutic applications in pigmentation disorders and skin aging.
Authors
- Wanxin Zeng (ORCID: https://orcid.org/0000-0001-7825-8026)
- Xi Wen (ORCID: https://orcid.org/0000-0002-4895-4757)
- Hao Wang (ORCID: https://orcid.org/0000-0001-6881-9977)
- Yidan Xu (ORCID: https://orcid.org/0000-0003-0490-3082)
- Huimiao Tang
- Xinyi Li
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Lasers in Surgery and Medicine
- Published
- 2025-12-21
- DOI
- https://doi.org/10.1002/lsm.70084
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00