Molecular and Clinical Analyses of Gene Fusions Identify Therapeutic Targets in Paired Primary and Metastatic Breast Cancer from the AURORA Program (BIG 14-01)

The AURORA gene fusion catalog may serve as a valuable resource for identifying targetable genetic alterations, thereby supporting the development of more effective therapeutic strategies for breast cancer.

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Publication Details

Journal
Clinical Cancer Research
Published
2025-12-22
DOI
https://doi.org/10.1158/1078-0432.ccr-25-2707
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
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article

Molecular and Clinical Analyses of Gene Fusions Identify Therapeutic Targets in Paired Primary and Metastatic Breast Cancer from the AURORA Program (BIG 14-01)

Diogo Martins-Branco, Giuseppe Curigliano, David Cameron, José A. Seoane et al.
Clinical Cancer Research
Breast Cancer Treatment Studies
article

Molecular and Clinical Analyses of Gene Fusions Identify Therapeutic Targets in Paired Primary and Metastatic Breast Cancer from the AURORA Program (BIG 14-01)

Diogo Martins-Branco, Giuseppe Curigliano, David Cameron, José A. Seoane, AL Guerrero-Zotano, Matteo Benelli, Alice Raimbault, David Venet, Thayane Crestani, Alexandre Irrthum, Christos Sotiriou, Chiara Biagioni, Florentine Hilbers, Gabriele Zoppoli, A. Vingiani, Philippe Aftimos, Elisa Agostinetto, Danai Fimereli, Arnau Llinas-Bertran, Mafalda Oliveira, Martine Piccart, Carmela Caballero, Einav Nili Gal-Yam, Ana Vivancos, Dario Romagnoli
article en

Abstract

The AURORA gene fusion catalog may serve as a valuable resource for identifying targetable genetic alterations, thereby supporting the development of more effective therapeutic strategies for breast cancer.

Clinical Cancer ResearchVol. 32(5)
Hebron University (PS), Université Libre de Bruxelles (BE), University of Milan (IT), Sheba Medical Center (IL), Institut Jules Bordet (BE), Edinburgh Cancer Research (GB), Breast International Group (BE), Vall d'Hebron Institut de Recerca (ES), Fundación Instituto Valenciano de Oncología (ES), Italian Oncology Group of Clinical Research (IT), Oncode Institute (NL), Vall d'Hebron Hospital Universitari (ES), Edinburgh Genomics (GB), Ospedale Policlinico San Martino (IT), Azienda Usl Toscana Centro (IT), Fondazione IRCCS Istituto Nazionale dei Tumori (IT), GEICAM – Spanish Breast Cancer Group (ES), Hospital of Prato (IT), University of Florence (IT), European Institute of Oncology (IT), University of Genoa (IT)
No poverty
Openalex Percentile: Top 35%
Breast Cancer Treatment Studies
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