Pain Assessment During Less Invasive Surfactant Administration Using Skin Conductance: A Prospective Cohort Study

ClinicalTrials.gov (NCT06150586) IMPACT: Skin conductance (SC) measurement has been proposed as an objective method for pain assessment in preterm infants. In our study, SC did not indicate a pain response in infants undergoing Less Invasive Surfactant Administration (LISA). Our findings suggest that SC alone may not be a reliable indicator of procedural pain in preterm infants shortly after birth. There remains a critical need for objective methods to assess pain in preterm infants. Further research is required to validate SC for neonatal pain assessment.