Novel magnetic resonance imaging insights from surgically confirmed temporal lobe encephaloceles support tethering as a potential mechanism of epileptogenesis
Careful review of preoperative imaging using two novel MRI indices may improve diagnosis of temporal encephaloceles. Our findings affirm the possibility that epileptogenicity of encephaloceles may be partly ascribed to temporal lobe tethering. Their early identification can refine surgical decision-making for patients with intractable, focal temporal lobe epilepsy.
Authors
- Richard Rammo (ORCID: https://orcid.org/0000-0002-8359-0880)
- Imad Najm (ORCID: https://orcid.org/0000-0001-5192-2089)
- Neha Sara John (ORCID: https://orcid.org/0000-0003-2415-5296)
- Demitre Serletis (ORCID: https://orcid.org/0000-0002-8037-9705)
- Baltazar Zavala (ORCID: https://orcid.org/0000-0002-7284-7994)
- Juan Bulacio (ORCID: https://orcid.org/0000-0002-2547-518X)
- Efstathios Kondylis (ORCID: https://orcid.org/0000-0002-6081-4503)
- Marina Feldman
- William Bingaman
Institutions
- Cleveland Clinic (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1002/epi.70062
- Primary Topic
- Head and Neck Surgical Oncology
- Type
- article
- Field-Weighted Citation Impact
- 0.00