Correlations between antiseizure medications and interictal epileptiform discharges in the idiopathic generalized epilepsies: A retrospective exploratory analysis of home video‐electroencephalographic studies

Carbamazepine is associated with increased interictal event rate, whereas the valproate and lamotrigine combination is associated with reduced interictal event rate and burden. Our findings also demonstrate that increased IED outcomes are associated with seizure occurrence.

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Publication Details

Journal
Epilepsia
Published
2025-12-22
DOI
https://doi.org/10.1002/epi.70072
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
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article

Correlations between antiseizure medications and interictal epileptiform discharges in the idiopathic generalized epilepsies: A retrospective exploratory analysis of home video‐electroencephalographic studies

Ewan S. Nurse, Omar Shadid, Philippa J Karoly, Basheer Arnaout et al.
Epilepsia
Epilepsy research and treatment
article

Correlations between antiseizure medications and interictal epileptiform discharges in the idiopathic generalized epilepsies: A retrospective exploratory analysis of home video‐electroencephalographic studies

Ewan S. Nurse, Omar Shadid, Philippa J Karoly, Basheer Arnaout, Mark J. Cook, Andrew Xu
article en

Abstract

Carbamazepine is associated with increased interictal event rate, whereas the valproate and lamotrigine combination is associated with reduced interictal event rate and burden. Our findings also demonstrate that increased IED outcomes are associated with seizure occurrence.

Epilepsia
The University of Melbourne (AU), St Vincent's Hospital Melbourne (AU)
Good health and well-being
Openalex Percentile: Top 37%
Epilepsy research and treatment
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