Hyperferritinemia Drives Risk: Unravelling the Association Between Ferritin Levels and Multi-Organ Dysfunction in Acute Febrile Illness: An Emergency Medicine Perspective

Mortality was highest among older patients and those with multiple organ involvement, neurological symptoms, respiratory distress, infections, or hemodynamic instability. Elevated serum ferritin levels were strongly correlated with increased mortality, multi-organ dysfunction, and prolonged hospital stays, reinforcing their prognostic value. Complications such as encephalitis, shock, myocarditis, and acute respiratory distress syndrome (ARDS) significantly increased mortality rates. Duration of hospitalization was also a critical determinant of survival.