The pediatric medical liver biopsy: indications, procedures, and histopathology

Pediatric liver biopsy is not limited to data gathered following formalin-fixation and paraffin-embedded liver tissue. It includes frozen tissue-based special stains, such as the oil red-O stain for lipids; a specimen devoted to ultrastructural analysis using a transmission electron microscope; and a flash-frozen tissue specimen used for future transcriptomics and genomic studies (e.g., single-nucleotide polymorphisms).