Are the CTV-to-PTV margins currently used in online adaptive radiotherapy for prostate cancer too large? The impact of the distribution of microscopic disease on treatment margin requirements

The CTV-to-PTV margins used in online adaptive radiotherapy for prostate cancer can be reduced by ∼2 mm, if the GTV is covered with an adequate margin.

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Publication Details

Journal
Radiotherapy and Oncology
Published
2025-12-20
DOI
https://doi.org/10.1016/j.radonc.2025.111351
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Are the CTV-to-PTV margins currently used in online adaptive radiotherapy for prostate cancer too large? The impact of the distribution of microscopic disease on treatment margin requirements

Floris J. Pos, Marcel van Herk, Tomas Janssen, Uulke A. van der Heide et al.
Radiotherapy and Oncology
Prostate Cancer Diagnosis and Treatment
article

Are the CTV-to-PTV margins currently used in online adaptive radiotherapy for prostate cancer too large? The impact of the distribution of microscopic disease on treatment margin requirements

Floris J. Pos, Marcel van Herk, Tomas Janssen, Uulke A. van der Heide, Marnix G. Witte, Mathijs G. Dassen
article en

Abstract

The CTV-to-PTV margins used in online adaptive radiotherapy for prostate cancer can be reduced by ∼2 mm, if the GTV is covered with an adequate margin.

Radiotherapy and OncologyVol. 216
The Netherlands Cancer Institute (NL), Oncode Institute (NL), The Christie NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 29%
Prostate Cancer Diagnosis and Treatment
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