Rational design of a kappa opioid receptor (KOR) peptide agonist with attenuated β-arrestin signaling

It contains 6 MD systems, including KOR^WT-Difelikefalin, KOR^WT-beta01, KOR^WT-cmp7, KOR^WT-cmp13, KOR^Y7.43A-Difelikefalin, KOR^Y7.43A-beta01. As for each system, 500 ns * 3 replications were performed.

Authors

Institutions

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-12-19
DOI
https://doi.org/10.5281/zenodo.17984758
Primary Topic
Neuropeptides and Animal Physiology
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Rational design of a kappa opioid receptor (KOR) peptide agonist with attenuated β-arrestin signaling

Center for structure and Function of Drug Targets State Key Laboratory of Receptor Research
Zenodo (CERN European Organization for Nuclear Research)
Neuropeptides and Animal Physiology
article

Rational design of a kappa opioid receptor (KOR) peptide agonist with attenuated β-arrestin signaling

Center for structure and Function of Drug Targets State Key Laboratory of Receptor Research
article en

Abstract

It contains 6 MD systems, including KOR^WT-Difelikefalin, KOR^WT-beta01, KOR^WT-cmp7, KOR^WT-cmp13, KOR^Y7.43A-Difelikefalin, KOR^Y7.43A-beta01. As for each system, 500 ns * 3 replications were performed.

Zenodo (CERN European Organization for Nuclear Research)
Shanghai Institute of Materia Medica (CN)
Openalex Percentile: Top 39%
Neuropeptides and Animal Physiology
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Rational design of a kappa opioid receptor (KOR) peptide agonist with attenuated β-arrestin signaling — Center for structure and Function of Drug Targets State Key Laboratory of Receptor Research · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS