Reaction of 1-Antipyryl-4-aroyl-5-methoxycarbonyl-1H-pyrrole-2,3-diones with Urea and Thiourea
Abstract Nucleophilic addition of urea and thiourea to 1-antipyryl-1 H -pyrrole-2,3-diones afforded 1-antipyryl-4-aroyl-3-hydroxy-5-methoxycarbonyl-5-ureido-1 H -pyrrol-2-ones and 1-antipyryl-4-aroyl-3-hydroxy-5-methoxycarbonyl-5-thioureido-1 H -pyrrol-2-ones. 1-Antipyryl-4-aroyl-3-hydroxy-5-methoxycarbonyl-5-ureido-1 H -pyrrol-2-ones underwent intramolecular spiro heterocyclization by the action of sodium methoxide.
Authors
- A. N. Maslivets
- V. A. Lyadov
- E. S. Denislamova
- D. E. Makrushin
Institutions
- Perm State University (RU)
- Perm National Research Polytechnic University (RU)
Publication Details
- Journal
- Russian Journal of Organic Chemistry
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1134/s1070428024601146
- Primary Topic
- Chemical synthesis and pharmacological studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00