Effectiveness and Safety of 75 mg and 150 mg Pregabalin for Postoperative Analgesia in Breast Cancer Surgery: A Randomized Double-Blinded Trial

Pregabalin is a safe drug and has good analgesic effect. Although the analgesic effectiveness of higher dose, i.e., 150 mg was better, adverse effect in terms of sedation was more. Hence, we suggest pregabalin 75 mg to be used preoperatively as it has demonstrated to have good analgesic effectiveness.

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Publication Details

Journal
International Journal of Applied and Basic Medical Research
Published
2025-10-01
DOI
https://doi.org/10.4103/ijabmr.ijabmr_179_25
Primary Topic
Anesthesia and Pain Management
Type
article
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0.00
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article

Effectiveness and Safety of 75 mg and 150 mg Pregabalin for Postoperative Analgesia in Breast Cancer Surgery: A Randomized Double-Blinded Trial

Geeta Mittal, M. Sashank
International Journal of Applied and Basic Medical Research
Anesthesia and Pain Management
article

Effectiveness and Safety of 75 mg and 150 mg Pregabalin for Postoperative Analgesia in Breast Cancer Surgery: A Randomized Double-Blinded Trial

Geeta Mittal, M. Sashank
article en

Abstract

Pregabalin is a safe drug and has good analgesic effect. Although the analgesic effectiveness of higher dose, i.e., 150 mg was better, adverse effect in terms of sedation was more. Hence, we suggest pregabalin 75 mg to be used preoperatively as it has demonstrated to have good analgesic effectiveness.

International Journal of Applied and Basic Medical ResearchVol. 15(4)
Dayanand Medical College & Hospital (IN), Asian Institute of Medical Sciences (IN), Public Works Department Buildings and Roads (IN), Satguru Partap Singh Hospital (IN)
Good health and well-being
Openalex Percentile: Top 28%
Anesthesia and Pain Management
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