Functionalization of 1,1′-Biadamantanes in Acidic Medium

Abstract Reactions of 1,1′-biadamantanes in nitric acid medium in the presence of nitrogen nucleophiles afforded a number of symmetrical difunctional derivatives. Reactions of 1,1′-biadamantane-3,3′-diols with carbon nucleophiles were carried out in sulfuric acid medium. A series of new tetra- and hexasubstituted functionalized 1,1′-biadamantane derivatives were synthesized in the system H 2 SO 4 –HNO 3 .