Lantapenoids A–C from the aerial parts of Vietnamese Lantana camara

Two new euphane-type triterpenoids, lantapenoids A and B ( 1–2 ), a new acyclic monoterpenoid, lantapenoid C ( 7 ), and four known triterpenoids ( 3–6 ), along with hispidulin ( 8 ) and 1,2,3-naphthalenetriol ( 9 ), were isolated from the dichloromethane extract of the aerial parts of Lantana camara Linn. Their structures were elucidated through extensive analyses of IR, HRESI-MS, 1D, and 2D NMR data, as well as comparison with the published data. In vivo bioassays showed that the dichloromethane extract suppressed Magnaporthe oryzae by 56 % at 3000 µg mL −1 , while fraction LD1108 (from the dichloromethane extract) exhibited 69 % inhibition against Phytophthora infestans at 2000 µg mL −1 . Among the nine metabolites, only compound 3 showed in vivo antifungal activity against M. oryzae, with 56 % inhibition at 1000 µg mL −1 . These results suggested the use of this plant extract and its metabolites as eco-friendly fungicidal agents for controlling plant fungal diseases. • Three new and six known compounds were isolated from the aerial parts of Lantana camara Linn. • Their chemical structures were elucidated by spectroscopic analyses. • The dichloromethane extract and a major metabolite exhibited significant in vivo antifungal activity, suppressing Magnaporthe oryzae and Phytophthora infestans up to 69 %.