Comparison of intravenous pethidine and sublingual buprenorphine on postoperative pain severity in patients with vertebral fracture surgery: a randomized multicenter, double-blind controlled trial

Sublingual buprenorphine does not differ from intravenous pethidine regarding pain intensity following vertebral fracture surgery; however, it is considered safer with fewer side effects. Furthermore, the trend of pain changes in both treatment groups did not show significant differences.

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Publication Details

Journal
Annals of Medicine and Surgery
Published
2025-12-19
DOI
https://doi.org/10.1097/ms9.0000000000004551
Primary Topic
Opioid Use Disorder Treatment
Type
article
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article

Comparison of intravenous pethidine and sublingual buprenorphine on postoperative pain severity in patients with vertebral fracture surgery: a randomized multicenter, double-blind controlled trial

Sajjad Najafi, Mobina Joursaraei, Saeed Kargar-Soleimanabad, Saeed Ehteshami et al.
Annals of Medicine and Surgery
Opioid Use Disorder Treatment
article

Comparison of intravenous pethidine and sublingual buprenorphine on postoperative pain severity in patients with vertebral fracture surgery: a randomized multicenter, double-blind controlled trial

Sajjad Najafi, Mobina Joursaraei, Saeed Kargar-Soleimanabad, Saeed Ehteshami, Ali Lasemi
article en

Abstract

Sublingual buprenorphine does not differ from intravenous pethidine regarding pain intensity following vertebral fracture surgery; however, it is considered safer with fewer side effects. Furthermore, the trend of pain changes in both treatment groups did not show significant differences.

Annals of Medicine and SurgeryVol. 88(2)
Mazandaran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 28%
Opioid Use Disorder Treatment
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