Assessment of RNA at SVR4 and Treatment Completion as Alternative Measures of Hepatitis C Cure for People Who Inject Drugs

Hepatitis C virus treatment guidance was updated to include sustained virologic response at 4-weeks post-treatment (SVR4) as an alternative measure of cure for select groups. Among a community-based sample of people who inject drugs receiving an accelerated test-and-treat protocol, results at treatment completion and SVR4 predicted those at 12-week post-treatment.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-12-09
DOI
https://doi.org/10.1093/ofid/ofaf737
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of RNA at SVR4 and Treatment Completion as Alternative Measures of Hepatitis C Cure for People Who Inject Drugs

David V. Glidden, Ryan D. Assaf, Claire McDonell, Meghan D. Morris et al.
Open Forum Infectious Diseases
Hepatitis C virus research
article

Assessment of RNA at SVR4 and Treatment Completion as Alternative Measures of Hepatitis C Cure for People Who Inject Drugs

David V. Glidden, Ryan D. Assaf, Claire McDonell, Meghan D. Morris, Brittney Ayala, Annie F. Luetkemeyer, Jaline Chan, Jeff McKinney, Jennifer C Price
article en

Abstract

Hepatitis C virus treatment guidance was updated to include sustained virologic response at 4-weeks post-treatment (SVR4) as an alternative measure of cure for select groups. Among a community-based sample of people who inject drugs receiving an accelerated test-and-treat protocol, results at treatment completion and SVR4 predicted those at 12-week post-treatment.

Open Forum Infectious DiseasesVol. 13(1)
University of California, San Francisco (US), San Francisco Medical Society (US), University of California San Francisco Medical Center (US), Universidad Católica de Santa Fe (AR), Center for Health and Gender Equity (US), Social Action (NG)
Good health and well-being
Openalex Percentile: Top 31%
Hepatitis C virus research
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