High-Dose REirradiation for In-Field Recurrent Lung Cancer in the THOrax (RETHO): Outcomes of a Phase 2 Prospective Clinical Trial

This trial showed that high-dose thoracic reirradiation for recurrent lung cancer is effective and achieved a good OS higher than our null hypothesis. It resulted in good LC and DFS with low toxicity.

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Publication Details

Journal
International Journal of Radiation Oncology*Biology*Physics
Published
2025-12-20
DOI
https://doi.org/10.1016/j.ijrobp.2025.12.024
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
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article

High-Dose REirradiation for In-Field Recurrent Lung Cancer in the THOrax (RETHO): Outcomes of a Phase 2 Prospective Clinical Trial

M. Duijm, Steven Petit, Erik D. van Werkhoven, J. Nuyttens et al.
International Journal of Radiation Oncology*Biology*Physics
Lung Cancer Diagnosis and Treatment
article

High-Dose REirradiation for In-Field Recurrent Lung Cancer in the THOrax (RETHO): Outcomes of a Phase 2 Prospective Clinical Trial

M. Duijm, Steven Petit, Erik D. van Werkhoven, J. Nuyttens, W. Schillemans, Eugenio Cammareri, Ria Cornelissen, J. Belderbos, P.V. Granton, J.L. Knegjens
article en

Abstract

This trial showed that high-dose thoracic reirradiation for recurrent lung cancer is effective and achieved a good OS higher than our null hypothesis. It resulted in good LC and DFS with low toxicity.

International Journal of Radiation Oncology*Biology*PhysicsVol. 124(5)
The Netherlands Cancer Institute (NL), Erasmus MC Cancer Institute (NL)
Good health and well-being
Openalex Percentile: Top 29%
Lung Cancer Diagnosis and Treatment
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