Solitary Fibrous Tumor of Uterine Cervix: A Rare Entity Mimicking Clinically as Carcinoma Cervix
Solitary fibrous tumors (SFTs) are a rare spindle cell neoplasm arising from mesenchymal cells. It was first described in the pleura. There are numerous reports that document their extrapleural locations. SFT involving the cervix is extremely rare and only a handful of cases have been reported in Indian and western literature. Previously, it was thought that SFT tumor cells differentiated from mesothelial cells into fibroblasts. With the advent of immunohistochemistry, it is revealed that tumor cells in SFT lack mesothelial characteristics but express CD34 and Bcl-2, suggesting that the tumor originates from mesenchymal tissue. Preoperative definitive diagnosis of SFT cervix is difficult.
Authors
- Neha Gupta (ORCID: https://orcid.org/0000-0001-9570-3988)
- Shirish Chandanwale (ORCID: https://orcid.org/0000-0002-7854-4564)
- Akshi Raj (ORCID: https://orcid.org/0000-0001-7251-579X)
- Madhuri Singh
Institutions
- Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN)
Publication Details
- Journal
- International Journal of Applied and Basic Medical Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.4103/ijabmr.ijabmr_160_25
- Primary Topic
- Soft tissue tumor case studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00