The efficacy and safety of tocilizumab in juvenile localised scleroderma patients: a retrospective cohort study in Eastern China

Tocilizumab appears to be a safe and effective adjunctive therapy for juvenile localised scleroderma, particularly when initiated early, as it reduces relapse risk and the need for prolonged glucocorticosteroid use. It remains a promising adjunct in refractory or severe cases requiring long-term management.

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Publication Details

Journal
Advances in Rheumatology
Published
2025-12-20
DOI
https://doi.org/10.1186/s42358-025-00511-1
Citations
1
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
1.47
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article

The efficacy and safety of tocilizumab in juvenile localised scleroderma patients: a retrospective cohort study in Eastern China

Yang Shen, Denghuan Chen, Dingyun Chen, Shouwei Hang et al.
1 citations
Advances in Rheumatology
Systemic Sclerosis and Related Diseases
1.47
article

The efficacy and safety of tocilizumab in juvenile localised scleroderma patients: a retrospective cohort study in Eastern China

Yang Shen, Denghuan Chen, Dingyun Chen, Shouwei Hang, Na Li, Xing Wang, Jing Shan, Daliang Xu, Yutong Gao, Xiaoliang He
article en
1 citations

Abstract

Tocilizumab appears to be a safe and effective adjunctive therapy for juvenile localised scleroderma, particularly when initiated early, as it reduces relapse risk and the need for prolonged glucocorticosteroid use. It remains a promising adjunct in refractory or severe cases requiring long-term management.

Advances in Rheumatology
The University of Sydney (AU)
Good health and well-being
Openalex Percentile: Top 13%
Systemic Sclerosis and Related Diseases
1.47
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