Tumor necrosis factor-α promotes abnormal glucose metabolism after acute pancreatitis by inducing islet β-cell apoptosis <i>via</i> Bax/Bcl-2/caspase-3 signaling pathway
TNF-α contributes to β-cell apoptosis and AGM in AP through the Bax/Bcl-2/caspase-3 signaling pathway, suggesting TNF-α as a potential therapeutic target for preventing AP-associated AGM.
Institutions
- Soochow University (CN)
- Taixing People's Hospital (CN)
- Taizhou First People's Hospital (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.3748/wjg.v31.i47.113205
- Citations
- 1
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01