Identification of factors conferring resistance to trastuzumab deruxtecan in advanced gastric cancer: a translational study from the single-arm, phase II, DESTINY-Gastric06 trial
These findings provide novel insights into mechanisms underlying T-DXd resistance and highlight potential therapeutic targets for overcoming T-DXd resistance in GC.
Institutions
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Burning Rock Biotech (China) (CN)
- Peking University International Hospital (CN)
- Ministry of Education (ET)
Publication Details
- Journal
- Precision Clinical Medicine
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1093/pcmedi/pbaf038
- Citations
- 1
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 1.05