The Future of Periodontal Healing: Leukocyte-Platelet Rich Fibrin as a Catalyst for Accelerated Palatal Wound Recovery

Free gingival grafts (FGG) are among the most frequently used periodontal therapy modalities to widen the width of keratinized tissue and to treat gingival recession. However, donor site problems, specifically delayed healing of palatal wounds, remain a clinical challenge. Platelet-rich fibrin is an autologous material filled with growth factors that have shown promising results in improving soft-tissue healing and reducing postsurgical discomfort. This case report describes the use of Leukocyte-Platelet Rich Fibrin (L-PRF) to enhance the healing of a palatal wound in a patient receiving FGG. A 26-year-old female patient had insufficient keratinized gingiva and underwent FGG harvesting from the palatal mucosa. After harvesting the graft, L-PRF was applied directly to the donor site in order to accelerate healing and reduce discomfort. The application of L-PRF at the donor site resulted in faster wound healing, with complete epithelization noted in 3 weeks. The patient reported very little pain and discomfort postprocedure. The use of L-PRF as an adjunct to treat palatal wounds after FGG appears to enhance soft-tissue healing and reduce patient complications. This case illustrates the potential role of L-PRF in improving postsurgery outcomes, and it thus promotes faster recovery in periodontal surgeries. Further studies are required to establish standardized practices and evaluate the long-term impact.