Cerebral diffusion of posaconazole in an experimental model of disseminated scedosporiosis
These findings suggest increased permeability of the blood-brain-barrier, possibly related to changes in IL or gene expression levels in the brain. Infection and the resulting inflammation should therefore be considered for therapeutic drug monitoring, especially in cases of cerebral infection.
Institutions
- Université de Tours (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université de Bretagne Occidentale (FR)
- Centre Hospitalier Universitaire de Tours (FR)
- Centre Hospitalier Universitaire d'Angers (FR)
- Université d'Angers (FR)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1016/j.biopha.2025.118918
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00