The Serum Lipid Profile of Hypertensive Patients in Isiala Mbano, Imo State, Nigeria

This research assessed the serum lipid profiles in patients with hypertension and explored their association with hypertension in Isiala Mbano, Imo State, Nigeria. A total of 127 participants, both male and female, aged 25 years and above, were recruited and divided into hypertensive (n = 80) and normotensive (n = 47) cohorts. Hypertension was identified based on the World Health Organization (WHO) guidelines after taking three consecutive blood pressure readings. Venous blood samples (5 mL) were collected in a sterile manner into plain tubes for biochemical evaluation. Serum concentrations of Total cholesterol (TC), Triglycerides (TG), High-density lipoprotein (HDL) cholesterol, and Low-density lipoprotein (LDL) cholesterol were measured using standardized enzymatic colorimetric techniques. TG exhibited a moderate positive correlation with both TC and HDL (p < 0.001). TC showed a strong positive correlation with HDL and LDL and a moderate positive correlation with TG (all p < 0.001). HDL presented a moderate positive correlation with TG and LDL (p < 0.001), while LDL demonstrated a moderate positive correlation with HDL and TG (p = 0.001). No noteworthy correlation was found between TG and LDL. The hypertensive individuals in this study displayed dyslipidaemic characteristics, with significant positive inter-correlations among different lipid fractions. It is recommended that routine lipid profile evaluations and the early treatment of dyslipidaemia be incorporated into hypertension management to diminish cardiovascular risk.