High CDCP1 Expression Reflects Immune and Stromal Remodeling and Oncogenic Signaling in Pancreatic Ductal Adenocarcinoma

CDCP1 defines a transcriptionally distinct PDAC subtype characterized by immune evasion, stromal depletion, and genomic instability. These findings highlight CDCP1 as a potential therapeutic target and biomarker reflecting interplay between oncogenic signaling and the TME.

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Publication Details

Journal
World Journal of Oncology
Published
2025-12-19
DOI
https://doi.org/10.14740/wjon2682
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

High CDCP1 Expression Reflects Immune and Stromal Remodeling and Oncogenic Signaling in Pancreatic Ductal Adenocarcinoma

World Journal of Oncology
Pancreatic and Hepatic Oncology Research
article

High CDCP1 Expression Reflects Immune and Stromal Remodeling and Oncogenic Signaling in Pancreatic Ductal Adenocarcinoma

article en

Abstract

CDCP1 defines a transcriptionally distinct PDAC subtype characterized by immune evasion, stromal depletion, and genomic instability. These findings highlight CDCP1 as a potential therapeutic target and biomarker reflecting interplay between oncogenic signaling and the TME.

World Journal of OncologyVol. 17(1)
Yokohama City University (JP)
Good health and well-being
Openalex Percentile: Top 32%
Pancreatic and Hepatic Oncology Research
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High CDCP1 Expression Reflects Immune and Stromal Remodeling and Oncogenic Signaling in Pancreatic Ductal Adenocarcinoma · World Journal of Oncology (2025) | TGRS Research Map | TGRS