IS ELEVATED HBA1C ASSOCIATED WITH POSTOPERATIVE COMPLICATIONS IN MIDFOOT CHARCOT RECONSTRUCTION? MYTH OR REALITY?

Introduction: Guidance from the Royal College of Anaesthetists suggests that patients with poorly controlled diabetes are at increased risk of peri-operative complications, wound related issues, and prolonged hospital stays. Nevertheless, surgery remains recommended in urgent and semi-urgent cases. This study aimed to compare post-operative outcomes in patients undergoing Midfoot Charcot reconstruction, stratified by pre-operative HbA1c levels. Method: Following local governance approval, we retrospectively reviewed patients who underwent midfoot Charcot reconstruction between January 2018 and December 2024. Patients were grouped based on pre-operative HbA1c: Group A (<69 mmol/mol) and Group B (≥69 mmol/mol). Procedures included urgent first-stage debridement, elective second-stage reconstruction or single-stage reconstruction. All patients were treated using standardised protocols involving deep tissue sampling, local antibiotic-eluting agents (Cerament G), and a short course of systemic antibiotics. Post-operative complications and outcomes were compared. Results: A total of 105 patients were analysed: 82 in Group A and 23 in Group B. Both groups were similar in age and BMI. The median HbA1c was 50.5 mmol/mol in Group A (range: 30–69) and 79 mmol/mol in Group B (range: 70–129). Post-operative complications occurred in 11 patients (13.4%) in Group A and 3 patients (13%) in Group B. Infections occurred in five patients in Group A, with three requiring returns to theatre. In Group B, three patients developed wound infections, but none required re-operation. One patient in Group A required major amputation; none in Group B did. Fourteen patients died during follow-up (10 in Group A, 3 in Group B), all beyond 30 days post-operatively and the cause was unrelated to surgery. Conclusion: There was no significant difference in post-operative morbidity, mortality, or complication rates between the groups. Elevated HbA1c should not be viewed as a contraindication to surgery in patients with complex diabetic foot pathology.

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Publication Details

Journal
Orthopaedic Proceedings
Published
2025-12-19
DOI
https://doi.org/10.1302/1358-992x.2025.17.010
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
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article

IS ELEVATED HBA1C ASSOCIATED WITH POSTOPERATIVE COMPLICATIONS IN MIDFOOT CHARCOT RECONSTRUCTION? MYTH OR REALITY?

Orthopaedic Proceedings
Diabetic Foot Ulcer Assessment and Management
article

IS ELEVATED HBA1C ASSOCIATED WITH POSTOPERATIVE COMPLICATIONS IN MIDFOOT CHARCOT RECONSTRUCTION? MYTH OR REALITY?

article en

Abstract

Introduction: Guidance from the Royal College of Anaesthetists suggests that patients with poorly controlled diabetes are at increased risk of peri-operative complications, wound related issues, and prolonged hospital stays. Nevertheless, surgery remains recommended in urgent and semi-urgent cases. This study aimed to compare post-operative outcomes in patients undergoing Midfoot Charcot reconstruction, stratified by pre-operative HbA1c levels. Method: Following local governance approval, we retrospectively reviewed patients who underwent midfoot Charcot reconstruction between January 2018 and December 2024. Patients were grouped based on pre-operative HbA1c: Group A (<69 mmol/mol) and Group B (≥69 mmol/mol). Procedures included urgent first-stage debridement, elective second-stage reconstruction or single-stage reconstruction. All patients were treated using standardised protocols involving deep tissue sampling, local antibiotic-eluting agents (Cerament G), and a short course of systemic antibiotics. Post-operative complications and outcomes were compared. Results: A total of 105 patients were analysed: 82 in Group A and 23 in Group B. Both groups were similar in age and BMI. The median HbA1c was 50.5 mmol/mol in Group A (range: 30–69) and 79 mmol/mol in Group B (range: 70–129). Post-operative complications occurred in 11 patients (13.4%) in Group A and 3 patients (13%) in Group B. Infections occurred in five patients in Group A, with three requiring returns to theatre. In Group B, three patients developed wound infections, but none required re-operation. One patient in Group A required major amputation; none in Group B did. Fourteen patients died during follow-up (10 in Group A, 3 in Group B), all beyond 30 days post-operatively and the cause was unrelated to surgery. Conclusion: There was no significant difference in post-operative morbidity, mortality, or complication rates between the groups. Elevated HbA1c should not be viewed as a contraindication to surgery in patients with complex diabetic foot pathology.

Orthopaedic ProceedingsVol. 107-B(SUPP_17)
Basildon Hospital (GB)
Good health and well-being
Openalex Percentile: Top 32%
Diabetic Foot Ulcer Assessment and Management
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IS ELEVATED HBA1C ASSOCIATED WITH POSTOPERATIVE COMPLICATIONS IN MIDFOOT CHARCOT RECONSTRUCTION? MYTH OR REALITY? · Orthopaedic Proceedings (2025) | TGRS Research Map | TGRS