Fructose consumption and metabolic hypertension in rats: a systematic review and meta-analysis

Animal studies suggest that fructose intake may contribute to elevated SBP, potentially increasing the risk of hypertension. While trends were observed across various doses and exposure durations, not all findings reached statistical significance. These observations highlight the importance of further research into the long-term effects of fructose on human blood pressure and their relevance to dietary guidelines and public health policies.

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Publication Details

Journal
PeerJ
Published
2025-12-19
DOI
https://doi.org/10.7717/peerj.20097
Primary Topic
Diet, Metabolism, and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Fructose consumption and metabolic hypertension in rats: a systematic review and meta-analysis

PeerJ
Diet, Metabolism, and Disease
article

Fructose consumption and metabolic hypertension in rats: a systematic review and meta-analysis

article en

Abstract

Animal studies suggest that fructose intake may contribute to elevated SBP, potentially increasing the risk of hypertension. While trends were observed across various doses and exposure durations, not all findings reached statistical significance. These observations highlight the importance of further research into the long-term effects of fructose on human blood pressure and their relevance to dietary guidelines and public health policies.

PeerJVol. 13
Monash University Malaysia (MY), INTI International University (MY), SRM Institute of Science and Technology (IN), University Kebangsaan Malaysia Medical Centre (MY), Mahsa University (MY), SRM University (IN), MNR Medical College and Hospital (IN), University of Wisconsin–La Crosse (US), Sunway University (MY)
Openalex Percentile: Top 32%
Diet, Metabolism, and Disease
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Fructose consumption and metabolic hypertension in rats: a systematic review and meta-analysis · PeerJ (2025) | TGRS Research Map | TGRS