Machine learning analysis of clinical, psychological and sociodemographic factors predicting mental well-being in patients with severe mental illness: Insights from the French REHABase cohort

Using advanced machine learning methodology on a large sample of patients with transdiagnostic exploration, our results showed both the crucial role of resilience and resistance to stigma in overall mental well-being and the critical importance of social contact in schizophrenia. These insights should help improve care trajectories for individuals with severe psychopathologies, particularly by promoting social cognitive remediation in schizophrenia.

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Publication Details

Journal
Comprehensive Psychiatry
Published
2025-12-19
DOI
https://doi.org/10.1016/j.comppsych.2025.152651
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Machine learning analysis of clinical, psychological and sociodemographic factors predicting mental well-being in patients with severe mental illness: Insights from the French REHABase cohort

Comprehensive Psychiatry
Schizophrenia research and treatment
article

Machine learning analysis of clinical, psychological and sociodemographic factors predicting mental well-being in patients with severe mental illness: Insights from the French REHABase cohort

article en

Abstract

Using advanced machine learning methodology on a large sample of patients with transdiagnostic exploration, our results showed both the crucial role of resilience and resistance to stigma in overall mental well-being and the critical importance of social contact in schizophrenia. These insights should help improve care trajectories for individuals with severe psychopathologies, particularly by promoting social cognitive remediation in schizophrenia.

Comprehensive PsychiatryVol. 145
Centre National de la Recherche Scientifique (FR), Fondation FondaMental (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre Hospitalier Universitaire de Limoges (FR), Institut des Sciences Cognitives Marc Jeannerod (FR), Centre Hospitalier Universitaire de Clermont-Ferrand (FR), Centre Hospitalier Le Vinatier (FR), Centre Hospitalier Henri Laborit (FR), Institut des Sciences Cognitives (FR), Centre Hospitalier Universitaire de Saint-Étienne (FR), Université de Limoges (FR)
Openalex Percentile: Top 37%
Schizophrenia research and treatment
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