Dapagliflozin in Acute Cardiovascular Conditions

No treatment effect heterogeneity was observed based on intensive care unit admission reason. Dapagliflozin use in critically ill cardiovascular patients appeared safe, demonstrating a modest diuretic effect with minimal vasoactive support increases, warranting further investigation. (Dapagliflozin in Patients With Critical Illness [DEFENDER]; NCT05558098).

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Publication Details

Journal
JACC Advances
Published
2025-12-19
DOI
https://doi.org/10.1016/j.jacadv.2025.102459
Citations
1
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
1.29
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article

Dapagliflozin in Acute Cardiovascular Conditions

1 citations
JACC Advances
Diabetes Treatment and Management
1.29
article

Dapagliflozin in Acute Cardiovascular Conditions

article en
1 citations

Abstract

No treatment effect heterogeneity was observed based on intensive care unit admission reason. Dapagliflozin use in critically ill cardiovascular patients appeared safe, demonstrating a modest diuretic effect with minimal vasoactive support increases, warranting further investigation. (Dapagliflozin in Patients With Critical Illness [DEFENDER]; NCT05558098).

JACC AdvancesVol. 5(1)
Instituto Federal da Bahia (BR), Faculdade de Medicina de São José do Rio Preto (BR), University of Alberta (CA), Hospital Israelita Albert Einstein (BR), Universidade Nove de Julho (BR), Centro Universitário Curitiba (BR), Australian and New Zealand Intensive Care Society (AU), Instituto de Ensino e Pesquisa Santa Casa (BR), Hospital de Câncer de Barretos (BR), Hospital Universitário Evangélico de Curitiba (BR), Hospital São Vicente (BR), Instituto de Tecnologia e Pesquisa (BR), Hospital de Clínicas Universidade Federal do Paraná (BR), Hospital Universitário de Brasília (BR), Hospital do Coração (BR), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR), Instituto de Neurologia de Curitiba (BR), Hospital de Base (BR), Hospital São Paulo (BR)
Good health and well-being
Openalex Percentile: Top 13%
Diabetes Treatment and Management
1.29
DOIOpen Access PDFOpenAlex
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Dapagliflozin in Acute Cardiovascular Conditions · JACC Advances (2025) | TGRS Research Map | TGRS