Network-based insights into miR-30a-5p-mediated regulation and EGCG targeting in triple-negative breast cancer

The results emphasizes that EGCG has strong binding affinity towards YWHAZ, revealing that miR-30a-EGCG targets TNBC synergistically through cell-cycle-mediated pathways. The findings give rational support for miRNA-guided phytochemical-based TNBC therapeutic development.

Institutions

Vellore Institute of Technology University (IN)

Publication Details

Journal: Frontiers in Bioinformatics
Published: 2025-12-19
DOI: https://doi.org/10.3389/fbinf.2025.1735106
Primary Topic: 14-3-3 protein interactions
Type: article
Field-Weighted Citation Impact: 0.00

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article

Network-based insights into miR-30a-5p-mediated regulation and EGCG targeting in triple-negative breast cancer

Dec 19, 2025

Frontiers in Bioinformatics

14-3-3 protein interactions

article

Network-based insights into miR-30a-5p-mediated regulation and EGCG targeting in triple-negative breast cancer

December 19, 2025article en

Abstract

Frontiers in BioinformaticsVol. 5

Vellore Institute of Technology University (IN)

Openalex Percentile: Top 37%

14-3-3 protein interactions

DOI Open Access PDF OpenAlex

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Network-based insights into miR-30a-5p-mediated regulation and EGCG targeting in triple-negative breast cancer · Frontiers in Bioinformatics (2025) | TGRS Research Map | TGRS