Colorectal cancer metastasis to the brain: A scoping review of incidence, treatment, and outcomes

Prognosis is influenced by tumor burden, performance status, and emerging molecular markers. Stereotactic radiotherapy and surgical resection provide favorable outcomes for select patients, whereas chemotherapy and immunotherapy remain areas of limited evidence. Continued research is needed to identify high-risk patients and optimize multidisciplinary treatment approaches.

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Publication Details

Journal
World Journal of Gastrointestinal Pathophysiology
Published
2025-12-19
DOI
https://doi.org/10.4291/wjgp.v16.i4.110961
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Colorectal cancer metastasis to the brain: A scoping review of incidence, treatment, and outcomes

World Journal of Gastrointestinal Pathophysiology
Brain Metastases and Treatment
article

Colorectal cancer metastasis to the brain: A scoping review of incidence, treatment, and outcomes

article en

Abstract

Prognosis is influenced by tumor burden, performance status, and emerging molecular markers. Stereotactic radiotherapy and surgical resection provide favorable outcomes for select patients, whereas chemotherapy and immunotherapy remain areas of limited evidence. Continued research is needed to identify high-risk patients and optimize multidisciplinary treatment approaches.

World Journal of Gastrointestinal PathophysiologyVol. 16(4)
University of Florida (US)
Openalex Percentile: Top 29%
Brain Metastases and Treatment
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Colorectal cancer metastasis to the brain: A scoping review of incidence, treatment, and outcomes · World Journal of Gastrointestinal Pathophysiology (2025) | TGRS Research Map | TGRS