Clinical Significance and Potential Molecular Mechanisms of Angiotensin-Converting Enzyme 2 in Colorectal Cancer

The upregulation of ACE2 is associated with nerve invasion, pathological type, and an immunosuppressive microenvironment with reduced CD8<sup>+</sup> T-cell infiltration and PD-L1 expression.

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Publication Details

Journal
World Journal of Oncology
Published
2025-12-19
DOI
https://doi.org/10.14740/wjon2650
Primary Topic
Renin-Angiotensin System Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical Significance and Potential Molecular Mechanisms of Angiotensin-Converting Enzyme 2 in Colorectal Cancer

World Journal of Oncology
Renin-Angiotensin System Studies
article

Clinical Significance and Potential Molecular Mechanisms of Angiotensin-Converting Enzyme 2 in Colorectal Cancer

article en

Abstract

The upregulation of ACE2 is associated with nerve invasion, pathological type, and an immunosuppressive microenvironment with reduced CD8<sup>+</sup> T-cell infiltration and PD-L1 expression.

World Journal of OncologyVol. 17(1)
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN), Yulin Orthopedics Hospital of Chinese and Western Medicine (CN)
Guangxi Medical University, Youth Science Foundation of Guangxi Medical University
Good health and well-being
Openalex Percentile: Top 32%
Renin-Angiotensin System Studies
DOIOpen Access PDFOpenAlex
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