Global Trends in MPOX Research (2014–2025): A Bibliometric Analysis and Overview

Lulu Xie,* Yimin Zhou,* Xinyu Zhang, Tian Lan, Wenchao Sun Wenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, 325035, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wenchao Sun, Email [email protected] Tian Lan, Email [email protected]: The 2022 global monkeypox outbreak fuelled a surge in related research. In this study, a bibliometric analysis of 2,076 monkeypox-related articles indexed in the Web of Science Core Collection (from January 2014 to June 2025) was performed, and VOSviewer was used to visualize keyword co-occurrence networks and collaboration patterns among countries and institutions. Unlike existing studies, the latest data for 2024– 2025 are incorporated; postoutbreak research trends, collaborative patterns, and PHEIC-driven resource aggregation effects are systematically incorporated; and gaps in dynamic and multifaceted analyses of the field are addressed. The results revealed a three-stage global research output: low accumulation (2014– 2021), a sharp surge after 2022, and sustained high levels after a peak in 2023. The core research clusters focused on viral transmission dynamics and clinical interventions. Country contributions showed a pyramidal hierarchy, with the US leading, followed by China, India, and Saudi Arabia; government health agencies and academic institutions codominated collaborations. The findings confirm the role of the PHEIC in concentrating scientific resources, emphasizing the importance of strengthening international collaboration to address future epidemic challenges.Keywords: MPOX, VOSviewer, co-occurrence networks, countries, institutions, outbreaks, bibliometric analysis, public health emergency