Hearing Loss in Young Adults: Risk Factors, Mechanisms and Prevention Models

Hearing loss is increasingly recognized as a major public health concern among young adults, who are traditionally considered a low-risk group. This narrative review synthesizes recent evidence on risk and aggravating factors of early-onset hearing impairment, including recreational and occupational noise exposure, genetic susceptibility, infections, ototoxic medications, and lifestyle contributors. Pathophysiological mechanisms include cochlear synaptopathy, oxidative stress, excitotoxicity, vascular compromise, and immune-mediated injury. Global Burden of Disease data and World Health Organization reports indicate that more than one billion young people are at risk due to unsafe listening practices. Studies highlight emerging risk factors such as hidden hearing loss, extended high-frequency impairment and associations with COVID-19. Aggravating factors include delayed diagnosis, cumulative exposures and lack of preventive strategies. Early detection via advanced audiological assessments, such as extended high-frequency audiometry, otoacoustic emissions, speech-in-noise testing and auditory brainstem responses, is critical to prevent permanent damage. Public health interventions-particularly safe listening campaigns, early screening and monitoring in high-risk populations-are essential to reduce long-term disability.

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Publication Details

Journal
Biomedicines
Published
2025-12-18
DOI
https://doi.org/10.3390/biomedicines13123116
Primary Topic
Hearing, Cochlea, Tinnitus, Genetics
Type
article
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article

Hearing Loss in Young Adults: Risk Factors, Mechanisms and Prevention Models

Biomedicines
Hearing, Cochlea, Tinnitus, Genetics
article

Hearing Loss in Young Adults: Risk Factors, Mechanisms and Prevention Models

article en

Abstract

Hearing loss is increasingly recognized as a major public health concern among young adults, who are traditionally considered a low-risk group. This narrative review synthesizes recent evidence on risk and aggravating factors of early-onset hearing impairment, including recreational and occupational noise exposure, genetic susceptibility, infections, ototoxic medications, and lifestyle contributors. Pathophysiological mechanisms include cochlear synaptopathy, oxidative stress, excitotoxicity, vascular compromise, and immune-mediated injury. Global Burden of Disease data and World Health Organization reports indicate that more than one billion young people are at risk due to unsafe listening practices. Studies highlight emerging risk factors such as hidden hearing loss, extended high-frequency impairment and associations with COVID-19. Aggravating factors include delayed diagnosis, cumulative exposures and lack of preventive strategies. Early detection via advanced audiological assessments, such as extended high-frequency audiometry, otoacoustic emissions, speech-in-noise testing and auditory brainstem responses, is critical to prevent permanent damage. Public health interventions-particularly safe listening campaigns, early screening and monitoring in high-risk populations-are essential to reduce long-term disability.

BiomedicinesVol. 13(12)
Iuliu Hațieganu University of Medicine and Pharmacy (RO), University of Medicine and Pharmacy of Craiova (RO), Victor Babeș University of Medicine and Pharmacy Timișoara (RO), University of Craiova (RO)
Good health and well-being
Openalex Percentile: Top 35%
Hearing, Cochlea, Tinnitus, Genetics
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Hearing Loss in Young Adults: Risk Factors, Mechanisms and Prevention Models · Biomedicines (2025) | TGRS Research Map | TGRS