International Poster Session

BackgroundWith advancements in high-resolution videoendoscopy and increased screening, incidental detection of small duodenal neuroendocrine tumors(D-NETs)has risen.The optimal treatment-radical surgical resection or local excision, including endoscopic resectionremains debated.Various endoscopic techniques are used based on tumor characteristics, and current guidelines recommend endoscopic resection for D-NETs10 mm.This study evaluates the feasibility of diagnostic endoscopic resection for grade 1 or 2 D-NETs, considering recent therapeutic advancements.Methods We retrospectively analyzed 40 grade 1 or 2 D-NETs diagnosed at a single tertiary referral center between January 2009 and July 2023, evaluating outcomes such as histopathology, complete resection, and lymph node metastasis rates. ResultsThe mean follow-up period was 59.06.8 months, and the average NET size was 7.40.8mm, with 80 of tumors being smaller than 10 mm.The largest NET measured 25 mm.Most NETs were grade 1(90) .Initially, only 17.5 of patients underwent surgical treatment.After endoscopic treatment, two additional surgical resections were performed, revealing no lymph node metastasis.No patients exhibited lymph node metastasis or local recurrence.Among endoscopic resections, ligation-assisted EMR achieved a 100 complete resection rate.One case of iatrogenic perforation occurred but was successfully managed with endoscopic clip closure.Conclusions Small-sized grade 1 and 2 D-NETs showed no lymph node or distant metastases.Diagnostic endoscopic resection could be recommended for these tumors, with ligation-assisted EMR preferred for those smaller than 10 mm. Duodenal NET Endoscopic resectionIP-2S Preoperative anemia is an independent prognostic factor for esophageal cancer patients who receive curative treatment