Successful treatment of a complex Skene’s gland cyst: a case report

This study aimed to offer important diagnostic insights and a sensible treatment plan for such challenging situations by presenting an incredibly unusual example of Skene's gland cyst. We described a 39-year-old woman who suffered dysuria for 20 years with an acute exacerbation. Her sexual life was normal, and she did not exhibit any other significant clinical symptoms. However, positron emission tomography/computed tomography (PET/CT) and imaging tests gave contradictory results, with the former creating a high suspicion of malignancy, while the latter indicated a benign tumor. After a multidisciplinary discussion, a cautious treatment approach was adopted. Finally, the patient underwent a diagnostic puncture, and bacteriology detection, along with histological analysis, ultimately confirmed the diagnosis of a Skene's gland cyst. Following needle puncture biopsy and subsequent antibiotic therapy, follow-up assessments revealed that the mass disappeared. Importantly, the patient's clinical symptoms completely resolved, and no complications were observed. This case highlighted that puncture biopsy coupled with drainage was a safe and efficacious method, especially when faced with the challenge of diagnosing and treating paraurethral cystic masses.