RSL3 Promotes STAT3 Ubiquitination to Induce Autophagy and Apoptosis in PARPi-Resistant Breast Cancer Cells

Our findings highlight RSL3 as a promising therapeutic agent and STAT3 as a potential target for treating PARPi-resistant breast cancer.

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Publication Details

Journal
Biomolecules
Published
2025-12-18
DOI
https://doi.org/10.3390/biom15121749
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

RSL3 Promotes STAT3 Ubiquitination to Induce Autophagy and Apoptosis in PARPi-Resistant Breast Cancer Cells

Biomolecules
Ferroptosis and cancer prognosis
article

RSL3 Promotes STAT3 Ubiquitination to Induce Autophagy and Apoptosis in PARPi-Resistant Breast Cancer Cells

article en

Abstract

Our findings highlight RSL3 as a promising therapeutic agent and STAT3 as a potential target for treating PARPi-resistant breast cancer.

BiomoleculesVol. 15(12)
Wenzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 29%
Ferroptosis and cancer prognosis
DOIOpen Access PDFOpenAlex
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RSL3 Promotes STAT3 Ubiquitination to Induce Autophagy and Apoptosis in PARPi-Resistant Breast Cancer Cells · Biomolecules (2025) | TGRS Research Map | TGRS