Association of Molar Dose and Early Retinochoroidal Blood Flow Changes After Intravitreal Anti-Vascular Endothelial Growth Factor Therapy

Aflibercept 8 mg produced a significant 30-minute reduction in ocular blood flow. Choroidal flow reduction was greater than with aflibercept 2 mg and negatively correlated with molar dose, suggesting a concentration-dependent hemodynamic effect.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-12-18
DOI
https://doi.org/10.1167/iovs.66.15.56
Primary Topic
Retinal Diseases and Treatments
Type
article
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article

Association of Molar Dose and Early Retinochoroidal Blood Flow Changes After Intravitreal Anti-Vascular Endothelial Growth Factor Therapy

Investigative Ophthalmology & Visual Science
Retinal Diseases and Treatments
article

Association of Molar Dose and Early Retinochoroidal Blood Flow Changes After Intravitreal Anti-Vascular Endothelial Growth Factor Therapy

article en

Abstract

Aflibercept 8 mg produced a significant 30-minute reduction in ocular blood flow. Choroidal flow reduction was greater than with aflibercept 2 mg and negatively correlated with molar dose, suggesting a concentration-dependent hemodynamic effect.

Investigative Ophthalmology & Visual ScienceVol. 66(15)
Kurume University (JP)
Good health and well-being
Openalex Percentile: Top 31%
Retinal Diseases and Treatments
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Association of Molar Dose and Early Retinochoroidal Blood Flow Changes After Intravitreal Anti-Vascular Endothelial Growth Factor Therapy · Investigative Ophthalmology & Visual Science (2025) | TGRS Research Map | TGRS