Trinuclear Manganese(II) Complex Based on Diisopropyl(pyridin-2-ylmethyl)phosphine Oxide

A new trinuclear manganese(II) carboxylate complex [Mn3L2(OAc)6] (I), where L is diisopropyl(pyridin-2-ylmethyl)phosphine oxide, was synthesized. The composition of complex I was confirmed by mass spectrometry, IR spectroscopy, and elemental analysis. The crystal structure of the complex was determined by X-ray diffraction (CCDC no. 2447670). The luminescence and cytotoxicity of I were studied in relation to M-HeLa and HuTu80 cancer cell lines and Chang Liver normal cell line It was found that compound I exhibited high cytotoxicity against the HuTu80 cancer cells.

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Publication Details

Journal
Russian Journal of Coordination Chemistry
Published
2025-09-01
DOI
https://doi.org/10.1134/s1070328425600950
Primary Topic
Metal complexes synthesis and properties
Type
article
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article

Trinuclear Manganese(II) Complex Based on Diisopropyl(pyridin-2-ylmethyl)phosphine Oxide

Russian Journal of Coordination Chemistry
Metal complexes synthesis and properties
article

Trinuclear Manganese(II) Complex Based on Diisopropyl(pyridin-2-ylmethyl)phosphine Oxide

article en

Abstract

A new trinuclear manganese(II) carboxylate complex [Mn3L2(OAc)6] (I), where L is diisopropyl(pyridin-2-ylmethyl)phosphine oxide, was synthesized. The composition of complex I was confirmed by mass spectrometry, IR spectroscopy, and elemental analysis. The crystal structure of the complex was determined by X-ray diffraction (CCDC no. 2447670). The luminescence and cytotoxicity of I were studied in relation to M-HeLa and HuTu80 cancer cell lines and Chang Liver normal cell line It was found that compound I exhibited high cytotoxicity against the HuTu80 cancer cells.

Russian Journal of Coordination ChemistryVol. 51(9)
St Petersburg University (RU), Kazan Scientific Center (RU), A.E. Arbuzov Institute of Organic and Physical Chemistry (RU)
Openalex Percentile: Top 32%
Metal complexes synthesis and properties
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