Visible-light-induced annulation of 4-aminocoumarins to tetrahydropyrimidine-fused coumarins and evaluation of their antitumor activities

A green and efficient synthetic route to novel tetrahydropyrimidine-fused coumarins has been established via a visible-light-induced multicomponent reaction of 4-aminocoumarins, N -arylglycines, and formaldehyde without exogenous photosensitizers.

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Publication Details

Journal
Green Chemistry
Published
2025-12-18
DOI
https://doi.org/10.1039/d5gc05261k
Primary Topic
Radical Photochemical Reactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Visible-light-induced annulation of 4-aminocoumarins to tetrahydropyrimidine-fused coumarins and evaluation of their antitumor activities

Green Chemistry
Radical Photochemical Reactions
article

Visible-light-induced annulation of 4-aminocoumarins to tetrahydropyrimidine-fused coumarins and evaluation of their antitumor activities

article en

Abstract

A green and efficient synthetic route to novel tetrahydropyrimidine-fused coumarins has been established via a visible-light-induced multicomponent reaction of 4-aminocoumarins, N -arylglycines, and formaldehyde without exogenous photosensitizers.

Green ChemistryVol. 28(3)
Shanxi Medical University (CN), University of South China (CN)
Openalex Percentile: Top 34%
Radical Photochemical Reactions
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Visible-light-induced annulation of 4-aminocoumarins to tetrahydropyrimidine-fused coumarins and evaluation of their antitumor activities · Green Chemistry (2025) | TGRS Research Map | TGRS