Capture of isoflurane from anaesthetised dogs and cats following methadone, medetomidine and ketamine

Background Volatile anaesthetic agents contribute to climate change and reducing this impact is a commendable ambition. We evaluated the efficiency of a veterinary capture device for isoflurane (VET-can/VET-dock, SageTech Veterinary) in anaesthetised cats and dogs. Methods Purposeful sampling was used to recruit enough animals undergoing isoflurane general anaesthesia to fill one VET-can to at least 95% capacity. The vaporiser and VET-can were weighed pre-and post-anaesthesia to determine in vivo mass transfer (MT) of isoflurane and water. Primary outcomes were capture efficiency (isoflurane delivered: desorbed, %) and in vivo mass transfer (MT). Secondary outcomes were associations between MT and patient characteristics and anaesthesia variables. Results Thirty anaesthetics (21 cats; 9 dogs) were required to fill the VET-can to capacity. There was an overall capture efficiency of 81% isoflurane and 4% water. In vivo MT was 86% (57-100). There was no correlation between patient characteristics or anaesthesia parameters and in vivo MT. Limitations Interchangeable use of sidestream and mainstream capnography resulted in a difference in times to end-tidal isoflurane 0%. Conclusions Capture efficiency was 81%. The device prevented a mean release of 3.2 kgCO2e for each 20-minute anaesthetic period, approximately the equivalent of 13 miles driven in an average UK car.

Publication Details

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Repository@Nottingham (University of Nottingham)
Published
2025-12-04
Primary Topic
Veterinary Pharmacology and Anesthesia
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article
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article

Capture of isoflurane from anaesthetised dogs and cats following methadone, medetomidine and ketamine

Repository@Nottingham (University of Nottingham)
Veterinary Pharmacology and Anesthesia
article

Capture of isoflurane from anaesthetised dogs and cats following methadone, medetomidine and ketamine

article en

Abstract

Background Volatile anaesthetic agents contribute to climate change and reducing this impact is a commendable ambition. We evaluated the efficiency of a veterinary capture device for isoflurane (VET-can/VET-dock, SageTech Veterinary) in anaesthetised cats and dogs. Methods Purposeful sampling was used to recruit enough animals undergoing isoflurane general anaesthesia to fill one VET-can to at least 95% capacity. The vaporiser and VET-can were weighed pre-and post-anaesthesia to determine in vivo mass transfer (MT) of isoflurane and water. Primary outcomes were capture efficiency (isoflurane delivered: desorbed, %) and in vivo mass transfer (MT). Secondary outcomes were associations between MT and patient characteristics and anaesthesia variables. Results Thirty anaesthetics (21 cats; 9 dogs) were required to fill the VET-can to capacity. There was an overall capture efficiency of 81% isoflurane and 4% water. In vivo MT was 86% (57-100). There was no correlation between patient characteristics or anaesthesia parameters and in vivo MT. Limitations Interchangeable use of sidestream and mainstream capnography resulted in a difference in times to end-tidal isoflurane 0%. Conclusions Capture efficiency was 81%. The device prevented a mean release of 3.2 kgCO2e for each 20-minute anaesthetic period, approximately the equivalent of 13 miles driven in an average UK car.

Repository@Nottingham (University of Nottingham)
Openalex Percentile: Top 29%
Veterinary Pharmacology and Anesthesia
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