The mechanistic role of gitogenin as a treatment for laryngeal cancer: a network pharmacology and experimental analysis
Using network pharmacology and experimental validation, it was demonstrated that GIT exerts potent anticancer effects on LC by targeting the PI3K-Akt axis. The present findings suggest the potential of GIT for treating LC.
Institutions
- Minzu University of China (CN)
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/fphar.2025.1663323
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Inner Mongolia