A metabolomics study reveals potential plasma biomarkers for predicting post-infarction left ventricular remodeling: findings from the metabolights database

In summary, our preliminary findings suggest that threonine, glycine, and histidine may merit further investigation as potential biomarkers for post-STEMI LVR, and their association with key pathophysiological pathways hints at possible mechanistic roles. Given the absence of clinical and demographic data, combined with the small and imbalanced sample (6 LVR vs. 55 Non-LVR patients), our findings should be interpreted as exploratory and hypothesis-generating. Their clinical predictive utility requires validation in larger, independent prospective cohorts.