Alcohol-clozapine synergism triggering rhabdomyolysis at subtoxic levels: a case report and literature review
In patients consuming clozapine after alcohol intake, dynamic monitoring of CK and myoglobin should be implemented regardless of whether toxicology results are within normal limits. Early implementation of blood purification can effectively disrupt the rhabdomyolysis-renal injury cascade, thereby securing a critical therapeutic window for clinical intervention.
Institutions
- Fudan University (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Frontiers in Toxicology
- Published
- 2025-12-17
- DOI
- https://doi.org/10.3389/ftox.2025.1692362
- Primary Topic
- Muscle and Compartmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00