CALLY index predicts survival and surgical outcomes in colorectal cancer

The preoperative CALLY index is a simple, cost-effective, and reliable prognostic biomarker for CRC, predicting both surgical outcomes and long-term survival. Incorporation of CALLY into risk stratification may complement TNM staging, optimize perioperative management, and inform individualized treatment strategies. Further validation in multicenter, prospective cohorts is required to confirm the generalizability of these findings.