Traditional and non-traditional behavioral tests demonstrate the attenuation of cognitive deficits by therapeutic hypothermia in a rat model of neonatal hypoxic–ischemic encephalopathy

These observations highlight the need for deeper understanding of the enduring social and cognitive consequences of neonatal HIE including cases where therapeutic hypothermia was administered. This can pave the way for the development of tailored interventions that enhance the ability of HIE survivors to navigate the complex social and cognitive landscape of adult life.