Lesion locations are associated with cognitive impairment after ischemic stroke in young adults

We show that lesion locations associated with poorer cognitive performance in young stroke patients are widely distributed, including cerebellar regions. This study showcases the complexity in the relationships between affected brain regions and cognitive symptoms, explaining the variability in post-stroke cognitive outcome.

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Publication Details

Journal
NeuroImage Clinical
Published
2025-12-17
DOI
https://doi.org/10.1016/j.nicl.2025.103930
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
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article

Lesion locations are associated with cognitive impairment after ischemic stroke in young adults

NeuroImage Clinical
Dementia and Cognitive Impairment Research
article

Lesion locations are associated with cognitive impairment after ischemic stroke in young adults

article en

Abstract

We show that lesion locations associated with poorer cognitive performance in young stroke patients are widely distributed, including cerebellar regions. This study showcases the complexity in the relationships between affected brain regions and cognitive symptoms, explaining the variability in post-stroke cognitive outcome.

NeuroImage ClinicalVol. 49
University Medical Center Groningen (NL), Radboud University Nijmegen (NL), Leiden University Medical Center (NL), Maastricht University Medical Centre (NL), Gelre Hospitals (NL), Catharina Ziekenhuis (NL), Medisch Spectrum Twente (NL), Medisch Centrum Leeuwarden (NL), Radboud University Medical Center (NL), Sint Franciscus Gasthuis (NL), Medisch Centrum Haaglanden (NL), Amphia Ziekenhuis (NL), Radboud Institute for Molecular Life Sciences (NL), Canisius-Wilhelmina Ziekenhuis (NL), Haga Hospital (NL), Elisabeth-TweeSteden Ziekenhuis (NL), Amsterdam University Medical Centers (NL), Rijnstate Hospital (NL), Jeroen Bosch Ziekenhuis (NL), University of Amsterdam (NL)
No poverty
Openalex Percentile: Top 38%
Dementia and Cognitive Impairment Research
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